“We used mathematical models and analytical methods to compare blood circulation, pressure and shear thinning, and yield stress between atherosclerotic patient and coronary bypass graft patients, considering cardiac contraction. Using CT scan, we created three-dimension model. This model will assist surgeon in selecting the appropriate coronary bypass method,” says Dr. Benchawan.

         This research project receives 1.3 million baht in fund from Mahidol University under research fund from fiscal budget year 2008-2009. Dr. Benchawan collaborated with Prof. E Ming Tung, Department of Physics, and Asst. Prof.Thanongchai Siriapisit Department of Radiology, Faculty of Medicine, Siriraj Hospital to carry out the research. Currently, the research project aims to reduce the amount of time it takes to produce coronary artery model. Patent is also on the way.

         “Coronary artery bypass is a surgical procedure to change the coronary artery or alter the path by using arteries or veins from elsewhere in the patient's body and grafted to the coronary arteries. This is to improve the atherosclerotic condition. The internal thoracic arteries, radial arteries and saphenous veins are commonly used in grafting,” Asst. Prof.Thanongchai Siriapisit added.

         Previous bypass procedure required surgical experience. Prediction of outcome was not possible. Thus, surgeon tends to graft as many as possible and at the easiest location possible, which may not be the best location. Subsequent surgery, at times, is necessary.

         This study will provide surgeon with blood flow model, which allows for preliminary bypass result screening prior to actual operation. The model will evaluate whether the graft will provide sufficient amount of blood to the cardiac muscle or not. The chance of patient requiring subsequent surgery will be reduced. It is expected that within 5-10 years, this model can be implemented in patients.

Post Date : July 10, 2009